Cancer Weekly
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Adenoma
Reports from Erasmus University advance knowledge in adenoma
November 4th, 2008
"Cushing's disease (CD) is a severe disorder characterized by chronic hypercortisolism due to an ACTH-secreting pituitary adenoma. Transsphenoidal adenomectomy is the treatment of choice in humans with CD, but recurrences occur frequently," scientists in Netherlands report. "Finding an effective and safe medical treatment for CD may improve long-term clinical outcome. The recent demonstration of expression of somatostatin receptor subtypes (mainly sst(5)) and dopamine receptor subtype 2 (D-2) in human corticotroph adenomas offers the possibility for medical treatment of CD with novel somatostatin analogs and dopamine agonists. Investigation of the effects of these drugs...
Source: Cancer Weekly (2008-11-04)
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