Cancer Weekly
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Apoptosis
Researchers at Medical University of Graz release new data on apoptosis
November 4th, 2008
"The basic mechanisms of trophoblast invasion are not completely understood. This may be due to the lack of suitable in vitro models which enable experimental modulation of this complex process," scientists writing in the journal Human Reproduction report. "In the present study, a three-dimensional co-culture model is used for comparing two factors considered to be implicated in the regulation of trophoblast invasion, the expression of HLA-G and apoptosis, in vitro and in vivo. Tissue fragments from human first trimester decidua parietalis were put in close contact with spheroids of AC-1M59 trophoblast/choriocarcinoma hybrid cells as a model of the invasive...
Source: Cancer Weekly (2008-11-04)
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