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Cancer Vaccines
Investigators at Cork University release new data on cancer vaccines
November 4th, 2008
According to a study from Cork, Ireland, "We aimed to identify mechanisms driving local recurrence in a model of breast-conserving surgery (BCS) for breast cancer. Breast cancer recurrence after BCS remains a clinically significant, but poorly understood problem." "We have previously reported that recurrent colorectal tumours demonstrate altered growth dynamics, increased metastatic burden and resistance to apoptosis, mediated by upregulation of phosphoinositide-3-kinase/Akt (PI3K/Akt). We investigated whether similar characteristics were evident in a model of locally recurrent breast cancer. Tumours were generated by orthotopic inoculation of 4T1 cells in two groups of...
Source: Cancer Weekly (2008-11-04)
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