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Cancer Vaccines
Studies from University of Pennsylvania further understanding of cancer vaccines
November 11th, 2008
According to recent research published in the journal Expert Review of Vaccines, "T-cell immunotherapy relies on the fundamental concept that tumor antigens exist and are presented in the context of MHC molecules for recognition by specific T cells capable of cytolysis. However, heterogeneous expression of most characterized tumor antigens limits the broad applicability of cancer vaccines that target such antigens." "Telomerase, on the other hand, represents a prototype of a universal tumor antigen due to both its expression by the vast majority of tumors and its inherent functional involvement in oncogenic transformation. Given these attractive features, the...
Source: Cancer Weekly (2008-11-11)
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