Cancer Weekly
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Cancer Gene Therapy
New research on cancer gene therapy from Peking Union Medical College summarized
November 11th, 2008
Investigators publish new data in the report 'Derlin-1 is overexpressed on the tumor cell surface and enables antibody-mediated tumor targeting therapy.' According to recent research published in the journal Clinical Cancer Research, "Tumor targeting therapy is one of the most promising strategies for anticancer treatment. Derlin-1 has been reported to participate in misfolded protein dislocation and integrates into the endoplasmic reticulum (ER) membrane to survey for such protein aggregates." "We elucidate herein that Derlin-1 can leak to the plasmalemma from the ER in tumor cells and may have clinical application as a novel cancer target in the hope of...
Source: Cancer Weekly (2008-11-11)
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