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Cancer Weekly

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Cancer Gene Therapy



University of Colorado, Department of Surgery publishes research in cancer gene therapy



November 11th, 2008

Researchers detail in 'Focal adhesion kinase controls aggressive phenotype of androgen-independent prostate cancer,' new data in cancer gene therapy. According to recent research from the United States, "Overexpression of focal adhesion kinase (FAK) has been well correlated with tumor development and/or the maintenance of tumor phenotype. In addition, inappropriate activation of the extracellular regulated kinase (ERK) signaling pathway is common to many human cancers."

"In the present study, we investigated the interplay between FAK and ERK in androgen-independent prostate cancer cells (PC3 and DU145 cells). We observed that suppression of FAK expression using small...


Source: Cancer Weekly (2008-11-11)

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