Cancer Weekly
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Immunization
Data on immunization published by investigators at Research Center
November 11th, 2008
Data detailed in 'Diterpenes drive Th1 polarization depending on IL-12' have been presented. According to recent research published in the journal International Immunopharmacology, "Sandaracopimaric acid and Sandaracopimaradiene-3beta-ol are diterpenes isolated from the heatwood of Cryptomeria japonica and are pharmacologically active substances. Dendritic cells (DC) are key antigen presenting cells (APC), which link innate and adaptive immunity, ultimately activating antigen-specific T cells." "We demonstrate that Sandaracopimaric acid and Sandaracopimaradiene-3beta-ol activate humans DC as documented by phenotypic and functional maturation and altered cytokine...
Source: Cancer Weekly (2008-11-11)
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