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Cancer Weekly

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Immunization



Scientists at Center for Cancer Research detail research in immunization



November 11th, 2008

Fresh data on immunization are presented in the report 'Increased immune responses in rhesus macaques by DNA vaccination combined with electroporation.' According to a study from the United States, "We used optimized DNA expression vectors to compare two gene delivery methodologies in rhesus macaques, namely direct DNA injection and in vivo adaptive constant-current electroporation via the intramuscular route. The use of in vivo electroporation increased levels of gene expression and immune responses."

"We used an optimized HIV gag expression plasmid to show the development of new cellular immune responses in SIV-infected animals controlling viremia. Furthermore, after...


Source: Cancer Weekly (2008-11-11)

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