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Cancer Weekly

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Immunization



Scientists at Sanofi Pasteur report research in immunization



November 11th, 2008

A new study, 'Gene profiling analysis of ALVAC infected human monocyte derived dendritic cells,' is now available. "The recombinant canarypox virus ALVAC is being extensively studied as vaccine vector for the development of new vaccine strategies against chronic infectious diseases and cancer. However, the mechanisms by which ALVAC initiates the immune response have not been completely elucidated," scientists in France report.

"In order to determine the type of innate immunity triggered by ALVAC, we characterized the gene expression profile of human monocyte derived dendritic cells (MDDCs) upon ALVAC infection. These cells are permissive to poxvirus infection and play a...


Source: Cancer Weekly (2008-11-11)

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