Cancer Weekly
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Angiogenesis
Data on angiogenesis reported by A.S. Arbab and co-researchers
November 11th, 2008
"This study investigated the factors responsible for migration and homing of magnetically labeled AC133(+) cells at the sites of active angiogenesis in tumor. AC133(+) cells labeled with ferumoxide-protamine sulfate were mixed with either rat glioma or human melanoma cells and implanted in flank of nude mice," scientists in the United States report. "An MRI of the tumors including surrounding tissues was performed. Tumor sections were stained for Prussian blue (PB), platelet-derived growth factor (PDGF), hypoxia-inducible factor-1 alpha (HIF-1 alpha), stromal cell derived factor-1 (SDF-1), matrix metalloproteinase-2 (MMP-2), vascular endothelial growth factor (VEGF),...
Source: Cancer Weekly (2008-11-11)
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