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Cancer Weekly

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Angiogenesis



Scientists at National Institutes of Health describe research in angiogenesis



November 11th, 2008

According to recent research from the United States, "Inhibiting angiogenesis has become a major therapeutic strategy for cancer treatment. To identify common intracellular mediators, we previously analyzed gene expression profiles of endothelial cells after treatment with angiogenesis inhibitors."

"Filamin A interacting protein 1-like (FILIPIL; previously known as down-regulated in ovarian concert) was identified as one of the genes up-regulated in endothelial cells in response to these inhibitors. However, the expression and function of FILIPIL protein is uncharacterized. Here, we provide the first description of the expression and specific subcellular localization of...


Source: Cancer Weekly (2008-11-11)

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