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Cancer Weekly

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Cancer Vaccines



Scientists at Charite University describe research in cancer vaccines



November 18th, 2008

Research findings, 'HLA typing demands for peptide-based anti-cancer vaccine,' are discussed in a new report. "Immunological treatment of cancer has made some very promising advances during the last years. Anti-cancer vaccination using peptides or peptide-pulsed dendritic cells and adoptive transfer of in vitro generated, epitope-specific T cells depend on a well-fitting interaction of HLA molecule and epitope," investigators in Berlin, Germany report.

"Accurate HLA-typing is a key factor for successful anti-cancer vaccination. No comprehensive data and no suggestion exist on the HLA-typing in this setting. We performed a systematic review of PubMed analyzing HLA-typing...


Source: Cancer Weekly (2008-11-18)

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