Oral Squamous Cell Carcinoma
Study results from Federal University of Minas Gerais broaden understanding of oral squamous cell carcinoma
Published in Cancer Weekly, November 18th, 2008
"The aim of this study was to describe the human mutS homolog 2 (hMSH2) and human mutL homolog 1 (hMLH1) immunoexpression in different areas of oral squamous cell carcinoma (OSCC) - central/superficial (C/S) and invasive tumor front (ITF) - in an attempt to verify if the histological grade of malignancy interferes in this expression. Forty-six samples of OSCC were analyzed histologically," scientists in Belo Horizonte, Brazil report.
"Twenty-six cases (56.5%) presented ITF. Histological grades of malignancy were evaluated in all samples, and immunohistochemistry was applied using specific antibodies against hMSH2 and hMLH1 proteins. Immunoexpression was...
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Source: Cancer Weekly (2008-11-18)
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