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Prostate Cancer

Research on prostate cancer detailed by scientists at Georgetown University

Published in Cancer Weekly, November 18th, 2008

"Docetaxel/estramustine is a known active regimen in hormone-refractory prostate cancer (HRPC). A phase II study was conducted to assess the safety and efficacy of docetaxel/estramustine combined with exisulind, an apoptotic antineoplastic drug," researchers in the United States report.

"Eighty men with chemotherapy-naive HRPC were enrolled in a multi-center, cooperative group study. The treatment regimen consisted of oral estramustine (280 mg 3 times daily for 5 days), docetaxel 70 mg/m(2), oral exisulind (250 mg twice daily), oral dexamethasone (8 mg twice daily for 3 days), and oral warfarin (2 mg daily). Seventy-five eligible patients were treated with a median of 6...

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