Cancer Weekly
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Adenocarcinoma
Researchers at University of Oxford have published new data on adenocarcinoma
November 18th, 2008
"Piwi proteins and their interaction with piRNAs have rapidly emerged as important contributors to gene regulation, indicating their crucial function in germline and stem cell development. However, data on the Hiwi 1 (Hiwi) gene, one of the four human Piwi homologues, are still scarce," scientists in Oxford, the United Kingdom report. "Therefore, we investigated the Hiwi mRNA expression in microdissected PDAC tissues from patients with ductal adenocarcinoma of the pancreas (PDAC) by quantitative real-time PCR and the protein expression by immunohistochemistry. Elevated levels of Hiwi mRNA transcripts were measured in 40 out of 56 tissues and a positive immunostaining of...
Source: Cancer Weekly (2008-11-18)
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