Cancer Weekly
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Adenocarcinoma
Study results from W.B. Huang and colleagues broaden understanding of adenocarcinoma
November 18th, 2008
"To study a-Methylacyl coenzyme A racemase (AMACR) expression in gastric intestinal-type adenocarcinoma and its precursors, we performed an immunohistochemical assay (using an avidin-biotin-peroxidase complex method) on 106 paraffin-embedded gastric mucosal biopsy samples and 25 gastrectomy samples (37 negative for dysplasia; 30 indefinite for dysplasia; 22 low-grade dysplasia; 25 high-grade dysplasia; and 34 invasive intestinal adenocarcinoma). The results showed that AMACR staining was uniformly negative in the groups negative for dysplasia and indefinite for dysplasia," investigators in People's Republic of China report. "Only 1 of 22 (4.5%) low-grade dysplasia...
Source: Cancer Weekly (2008-11-18)
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