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Cancer Weekly

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Ameloblastoma



Scientists at Okayama University publish new data on ameloblastoma



November 18th, 2008

Researchers in Okayama, Japan conducted a study "To study the stromal variation and role of stromal-tumour cell interaction in impaired bone formation as well as enhanced bone resorption in ameloblastoma. Four types of stroma were observed histologically; fibrous, desmoplastic, myxoid and myxoid with hyalinization."

"Osteoblast and osteoclast were counted using haematoxylin and eosin sections and immunohistochemistry with CD68. After histomorphometric analysis, only fibrous and myxoid types of stroma were distinctly identified. Secreted frizzled-related peptide (sFRP)-2, transforming growth factor-beta 1 and receptor activator of nuclear factor-kappa B ligand (RANKL)...


Source: Cancer Weekly (2008-11-18)

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