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Bone Research
New findings from Musculoskeletal Disease Center in the area of bone research published
November 25th, 2008
Fresh data on bone research are presented in the report 'LMP-1 retroviral gene therapy influences osteoblast differentiation and fracture repair: a preliminary study.' "LIM mineralization protein-1 (LMP-1) is a novel intracellular osteogenic factor associated with bone development that has been implicated in the bone morphogenetic protein (BMP) pathway. This preliminary study evaluated the possibility of LMP-1-based retroviral gene therapy to stimulate osteoblast differentiation in vitro and fracture repair in vivo," investigators in the United States report. "A Moloney leukemia virus (MLV)-based retroviral vector to express LMP-1 with a hemagglutinin (HA) tag was...
Source: Cancer Weekly (2008-11-25)
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