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Cancer Weekly

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Adenocarcinoma



Data on enzyme research reported by researchers at Uniformed Services University of the Health Sciences, Medical Department



November 25th, 2008

"To elucidate the cellular localization of Phosphoglycerate mutase (PGAM1) type B in the brain and periphery, immunocytochemical studies were performed. The purified antigen used to generate the antiserum to PGAM1 was run on an SDS-PAGE gel, stained with coomassie blue, which yielded one sharp band at 29 kDa," scientists in the United States report.

"Immunocytochemistry of formalin perfused rats revealed distinct localization of PGAM1 in the endothelium of the capillaries and arteries of the brain, liver and kidneys. Since enhanced glycogenesis is a well-known characteristic of cancer cells, it is of interest that sustained angiogenesis is a hallmark that distinguishes...


Source: Cancer Weekly (2008-11-25)

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