Cancer Weekly
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Angiogenesis
Research from S. Jain and co-researchers in the area of angiogenesis published
November 25th, 2008
According to recent research published in the journal Cancer Research, "In cancer management, the cyclooxygenase (COX)-targeted approach has shown great promise in anticancer therapeutics. However, the use of COX-2 inhibitors has side effects and health hazards; thus, targeting its major metabolite prostaglandin E-2 (PGE(2))-mediated signaling pathway might be a rational approach for the next generation of cancer management." "Recent studies on several in vitro and in vivo models have revealed that elevated expression of COX-2 correlates with prostate tumor growth and angiogenesis. In this study, we have shown the in-depth molecular mechanism and the PGE(2)...
Source: Cancer Weekly (2008-11-25)
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