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Nerve Sheath Tumors

Reports from A. Zarineh and colleagues advance knowledge in nerve sheath tumors

Published in Cancer Weekly, November 25th, 2008

According to recent research published in the American Journal of Surgical Pathology, "Hybrid peripheral nerve sheath tumors (PNSTs) are recently recognized, rarely reported entities. Very few hybrid PNSTs with elements of perineurioma have been reported."

"We report a case of a 47-year-old man who presented with multiple (> 20) cutaneous nodules on all 4 extremities, present since childhood. The patient and his family had no history of other PNSTs, other neural-origin tumors, or genetic disorders, including neurofibromatosis. Five excised lesions are well circumscribed but unencapsulated nodular tumors composed of cytologically bland spindled cells with...

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