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Atherosclerosis
Research from Dongguk University has provided new data on atherosclerosis
November 25th, 2008
According to recent research from South Korea, "Vascular smooth-muscle cell (VSMC) proliferation plays a vital role in hypertension, atherosclerosis and restenosis. It has been reported that emodin, an active component extracted from rhubarb, can stop the growth of cancer cells; however, it is not known if emodin exerts similar anti-atherogenic effects in TNF-alpha treated human aortic smooth-muscle cells (HASMC)." "In this study, emodin treatment showed potent inhibitory effects in TNF-alpha-induced HASMC proliferation that were associated with induced apoptosis, including the cleavage of poly ADPribose polymerase (PARP). Moreover, inhibitors of caspase-3, -8 and -9...
Source: Cancer Weekly (2008-11-25)
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