Cancer Weekly
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Biopsy
New biopsy findings from University of Sao Paulo, Medical Department described
November 25th, 2008
According to a study from Botucatu, Brazil, "The aim of the present study was to examine the impact of polymorphisms in prostate-specific antigen (PSA) and androgen-related genes (AR, CYP17, and CYP19) on prostate cancer (PCa) risk in selected high-risk patients who underwent prostate biopsy. Blood samples and prostate tissues were obtained for DNA analysis." "Single-nucleotide polymorphisms in the 50-untranslated regions (UTRs) of the PSA (substitution A> G at position -158) and CYP17 (substitution T> C at 50-UTR) genes were detected by polymerase chain reaction (PCR)-restriction fragment length polymorphism assays. The CAG and TTTA repeats in the AR and CYP19...
Source: Cancer Weekly (2008-11-25)
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