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Cancer Weekly

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Brain Cancer



Research from Johns Hopkins University, Medical Department broadens understanding of brain cancer



November 25th, 2008

According to recent research from the United States, "Amide proton transfer (APT) imaging is a type of chemical exchange-dependent saturation transfer (CEST) magnetic resonance imaging (MRI) in which amide protons of endogenous mobile proteins and peptides in tissue are detected. Initial studies have shown promising results for distinguishing tumor from surrounding brain in patients, but these data were hampered by magnetic field inhomogeneity and a low signal-to-noise ratio (SNR)."

"Here a practical six-offset APT data acquisition scheme is presented that, together with a separately acquired CEST spectrum, can provide B-0-inhomogeneity corrected human brain APT images...


Source: Cancer Weekly (2008-11-25)

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