Cancer Weekly
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Brain Cancer
Studies from Pennsylvania State University, Medical Department provide new data on brain cancer
November 25th, 2008
According to recent research from the United States, "Immunotherapy of established solid tumors is rarely achieved, and the mechanisms leading to success remain to be elucidated. We previously showed that extended control of advanced-stage autochthonous brain tumors is achieved following adoptive transfer of naive C57BL/6 splenocytes into sublethally irradiated line SV11. mice expressing the SV40 T Ag (T Ag) oncoprotein, and was associated with in vivo priming of CD8(+) T cells (T-CD8) specific for the dominant epitope IV (T Ag residues 404-411)." "Using donor lymphocytes derived from mice that are tolerant to epitope IV or a newly characterized transgenic mouse line...
Source: Cancer Weekly (2008-11-25)
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