Cancer Weekly
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Angiogenesis
Studies from University of Illinois describe new findings in angiogenesis
December 2nd, 2008
A report, 'uPA/uPAR downregulation inhibits radiation-induced migration, invasion and angiogenesis in IOMM-Lee meningioma cells and decreases tumor growth in vivo,' is newly published data in International Journal of Oncology. "Meningioma is a well-known tumor of the central nervous system, and is treated by surgical resection and/or radiation. Recently, ionizing radiation has been shown to enhance invasiveness of surviving tumor cells, and several proteolytic enzyme molecules, including urokinase plasminogen activator (uPA), seem to be upregulated after radiation. uPA and its receptor (uPAR) have been strongly implicated in tumor invasion, angiogenesis and progression,"...
Source: Cancer Weekly (2008-12-02)
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