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Cancer Gene Therapy
New findings from Hirosaki University in the area of cancer gene therapy described
December 2nd, 2008
Investigators publish new data in the report 'Claudin-1 expression is induced by tumor necrosis factor-alpha in human pancreatic cancer cells.' "Claudin-1 is a membrane protein with four transmembrane domains, that is exclusively localized at cellular tight junctions. Recent studies have reported that claudin-1 plays an important role in cancer invasion and metastasis," scientists writing in the International Journal of Molecular Medicine report. "However, the significance of claudin-1 in pancreatic cancer is still unknown. In the present study, we investigated the role of claudin-1 expression in pancreatic cancer growth using the PANC-1 human pancreatic cancer...
Source: Cancer Weekly (2008-12-02)
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