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Cancer Weekly

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Gene Therapy



Researchers from Yonsei University, Division of Nuclear Medicine publish findings in gene therapy



December 2nd, 2008

Scientists discuss in 'Imaging of viral thymidine kinase gene expression by replicating oncolytic adenovirus and prediction of therapeutic efficacy' new findings in gene therapy. According to recent research from Seoul, Korea, "We have used a genetically attenuated adenoviral vector which expresses HSVtk to assess the possible additive role of suicidal gene therapy for enhanced oncolytic effect of the virus. Expression of TK was measured using a radiotracer-based molecular counting and imaging system."

"Replication-competent recombinant adenoviral vector (Ad-DeltaE1B19/55) was used in this study, whereas replication-incompetent adenovirus (Ad-DeltaE1A) was generated as...


Source: Cancer Weekly (2008-12-02)

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