Myeloma

Report summarizes myeloma study findings from A.P.D. Demasi and co-researchers

Published in Cancer Weekly, December 2nd, 2008

"Plasmablastic lymphoma (PBL) and multiple myeloma (MM) are B cell-derived malignancies that share many morphologic and immunophenotypic traits, making the differential diagnosis particularly complicated. We have recently demonstrated that peroxiredoxin I (PrdxI) is expressed in plasma cells but not in B lymphocytes, suggesting that its expression is development-associated," scientists in Campinas, Brazil report.

"To analyze PrdxI expression in PBL and in MM in order to study its utilization as an additional diagnostic molecular tool. Eight cases of PBL and nine of MM were studied by immunohistochemistry. We have demonstrated that PrdxI expression is closely connected...

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Source: Cancer Weekly (2008-12-02)

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