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Cancer Weekly

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Acute Myeloid Leukemia



Investigators at University of Tor Vergata have published new data on acute myeloid leukemia



December 2nd, 2008

" Despite the identification of several baseline prognostic indicators, the outcome of patients with acute myeloid leukemia (AML) is generally heterogeneous. The effects of autologous (AuSCT) or allogeneic stem-cell transplantation (SCT) are still under evaluation," investigators in Rome, Italy report.

"Minimal residual disease (MRD) states may be essential for assigning patients to therapy-dependent risk categories. Patients and Methods By multiparametric flow cytometry, we assessed the levels of MRD in 142 patients with AML who achieved complete remission after intensive chemotherapy. A level of 3.5 x 10(-4) residual leukemia cells (RLCs) after consolidation therapy...


Source: Cancer Weekly (2008-12-02)

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