Cancer Weekly
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Angiogenesis
Findings from F. Milde et al in angiogenesis reported
December 2nd, 2008
According to recent research from Zurich, Switzerland, "Recent advances in cancer research have identified critical angiogenic signaling pathways and the influence of the extracellular matrix on endothelial cell migration. These findings provide us with insight into the process of angiogenesis that can facilitate the development of effective computational models of sprouting angiogenesis." "In this work, we present the first three-dimensional model of sprouting angiogenesis that considers explicitly the effect of the extracellular matrix and of the soluble as well as matrix-bound growth factors on capillary growth. The computational model relies on a hybrid...
Source: Cancer Weekly (2008-12-02)
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