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Cancer Weekly

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Angiogenesis



Research from Chiba University, Medical Department reveals new findings on angiogenesis



December 2nd, 2008

"Endoglin, a component of the transforming growth factor beta receptor expressed in embryonic vascular endothelial cells, is expressed in vascular endothelial cells in several types of cancer tissues and is involved in tumor angiogenesis. The aim of this study was to analyze the expression pattern of endoglin in pancreatic cancer and assess the involvement of this molecule in cancer progression," researchers in Chiba, Japan report.

"Pancreatic cancer and adjacent normal tissues obtained from 36 patients were subjected to immunostaining with anti-endoglin antibody, and the microvessel density (MVD) was assessed based on the number of endoglin-positive vessels. Endoglin...


Source: Cancer Weekly (2008-12-02)

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