Cancer Weekly
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BMC Cancer
Data on BMC cancer published by researchers at University of Munich
December 2nd, 2008
According to recent research from Munich, Germany, "The intermediate filament forming protein keratin 8 (K8) is a tumour-associated antigen, which was shown to be over-expressed in a variety of malignancies. Here, we present a study of K8 expression in squamous epithelia of the head and neck area, including normal mucosa, hyperplastic and dysplastic leukoplakia, carcinomas of different sub-localisations, and lymph node metastases." "K8 expression was assessed upon immunohistochemistry with specific antibodies in cryosections of primary tumours of the head and neck area. K8 expression was characteristic of transformed tissue and marked early stages of disease, i.e....
Source: Cancer Weekly (2008-12-02)
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