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Osteosarcoma Gene Therapy

New osteosarcoma gene therapy study findings have been reported by researchers at China Medical University

Published in Cancer Weekly, December 2nd, 2008

Researchers detail in 'DDTD, an isoflavone derivative, induces cell apoptosis through the reactive oxygen species/apoptosis signal-regulating kinase 1 pathway in human osteosarcoma cells,' new data in osteosarcoma. "Osteosarcoma is the most common primary bone tumor associated with childhood and adolescence. In the present study, we investigated the anticancer effect of a new isoflavone derivative, 3',4'-dichloro-3-(3,4-dichlorophenylacetyl)-2,4,6-trihydroxydeoxybenzoin (DDTD) in human osteosarcoma cells," investigators in Taichung, Taiwan report.

"DDTD induced cell apoptosis in human osteosarcoma cell lines (including: U2OS, MG-63, Saos2 and ROS 17/2.8). We found that...

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