Cancer Weekly
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Cancer Vaccines
Research on cancer vaccines reported by A. Berntsen et al
December 2nd, 2008
"Therapeutic dendritic cell (DC) vaccination against cancer is a strategy aimed at activating the immune system to recognize and destroy tumor cells. In this nonrandomized phase 1/2 trial, we investigated the safety, feasibility, induction of T-cell response, and clinical response after treatment with a DC- based vaccine in patients with metastatic renal cell carcinoma," researchers in Herlev, Denmark report. "Twenty-seven patients with progressive cytokine-refractory metastatic renal cell carcinoma were vaccinated with DCs loaded with either a cocktail of survivin and telomerase peptides or tumor lysate depending on their HLA-A2 haplotype, and low-dose IL-2 was...
Source: Cancer Weekly (2008-12-02)
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