Cancer Weekly
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Cancer Vaccines
Study findings on cancer vaccines are outlined in reports from K. Kronenberger and colleagues
December 2nd, 2008
According to recent research from Munich, Germany, "B cell-derived chronic lymphocytic leukemia (CLL) is an incurable disease that requires innovative therapeutic regimens. Experimental approaches of immunotherapy aiming at induction of systemic T-cell responses have been developed." "Trioma cells provide a potent vaccine derived from malignant B cells that allows multiple antigens (Ags) from the parental tumor to be ingested by Ag-presenting cells. Like other strategies using modified whole tumor cells, this approach induces polyvalent responses. Using trioma cell-pulsed dendritic cells (DCs) for T-cell activation in vitro, we asked whether specific Ags over-expressed...
Source: Cancer Weekly (2008-12-02)
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