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Cancer Gene Therapy
Researchers from Charite University, Max Delbruck Center for Molecular Medicine discuss findings in cancer gene therapy
December 9th, 2008
New investigation results, 'Novel jet-injection technology for nonviral intratumoral gene transfer in patients with melanoma and breast cancer,' are detailed in a study published in Clinical Cancer Research. "This phase I clinical trial evaluated safety, feasibility, and efficiency of nonviral intratumoral jet-injection gene transfer in patients with skin metastases from melanoma and breast cancer. Seventeen patients were enrolled," investigators in Berlin, Germany report. "The patients received five jet injections with a total dose of 0.05 mg beta-galactosidase (LacZ)-expressing plasmid DNA (pCMVbeta) into a single cutaneous lesion. Clinical and laboratory...
Source: Cancer Weekly (2008-12-09)
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