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Gene Therapy
Studies from University of California, Department of Neurosurgery in the area of gene therapy published
December 9th, 2008
Current study results from the report, 'Murine retroviruses re-engineered for lineage tracing and expression of toxic genes in the developing chick embryo,' have been published. "We describe two replication incompetent retroviral vectors that co-express green fluorescent protein (GFP) and beta-galactosidase. These vectors incorporate either the avian reticuloendotheliosis (spleen necrosis virus; SNV) promoter or the chick beta-actin promoter, into the backbone of the murine leukemia (MLV) viral vector," investigators in the United States report. "The additional promoters drive transgene expression in avian tissue. The remainder of the vector is MLV-like, allowing high...
Source: Cancer Weekly (2008-12-09)
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