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Human Papillomavirus Gene Therapy
New findings in human papillomavirus gene therapy described from Chung-Shan Medical University
December 9th, 2008
Research findings, 'Human telomerase reverse transcriptase activated by E6 oncoprotein is required for human papillomavirus-16/18-infected lung tumorigenesis,' are discussed in a new report. "Our recent report indicates that human papillomavirus (HPV)-16/18 E6 oncoprotein is expressed in lung tumors and is related to p53 inactivation. We further explored whether human telomerase reverse transcriptase (hTERT) transcription is up-regulated by E6 and contributes to lung tumor development," scientists writing in the journal Clinical Cancer Research report. "Immunohistochemistry detected HPV-16 E6 oncoprotein in 135 lung tumors, and hTERT mRNA was evaluated by...
Source: Cancer Weekly (2008-12-09)
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