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Cancer Gene Therapy
New cancer gene therapy study findings have been reported by researchers at Technical University of Munich
December 9th, 2008
According to a study from Munich, Germany, "Pancreatic cancer is one of the most common causes of cancer death in Western civilization and the 5-year survival rate is below 5%. To improve the prognosis of pancreatic cancer, there is the need to develop effective nonsurgical treatment options for the disease." "In particular, in vivo models to validate potential targets at the genetic level are required. In this study we demonstrate that RCAS-mediated retroviral gene transfer into orthotopic pancreatic cancer tumor grafts is feasible. Furthermore, we show effective RCAS-dependent RNA interference in vivo. We validate in vivo bioluminescence imaging as a reliable tool to...
Source: Cancer Weekly (2008-12-09)
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