Cancer Weekly
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Angiogenesis
Reports from University of Dundee add new data to research in angiogenesis
December 9th, 2008
" To quantify vascularity in periradicular granulomas using different endothelial markers, and assess its value as an index of angiogenesis by comparing granulomas with healthy periodontal ligament (PDL). To use oral tumours, compared with adjacent normal mucosa, as positive controls," scientists writing in the International Endodontic Journal report. " Paraffin-embedded sections were stained with antibodies to von Willebrand factor (vWF), a pan-endothelial marker, and CD105, a putative marker for angiogenic vessels. Vascularity was quantified by different methods reflecting vessel volume and density. Irrespective of the marker or method used, vascularity values...
Source: Cancer Weekly (2008-12-09)
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