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Cancer Weekly

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Angiogenesis



Research conducted at Washington University, Medical Department has provided new information about angiogenesis



December 9th, 2008

According to recent research from the United States, "Angiogenesis is a critical early feature of atherosclerotic plaque development and may also feature prominently in the pathogenesis of aortic valve stenosis. It has been shown that MRI can detect and quantify specific molecules of interest expressed in cardiovascular disease and cancer by measuring the unique fluorine signature of appropriately targeted perfluorocarbon (PFC) nanoparticles."

"In this study, we demonstrated specific binding of alpha(v)beta(3) integrin targeted nanoparticles to neovasculature in a rabbit model of aortic valve disease. We also showed that fluorine MRI could be used to detect and quantify...


Source: Cancer Weekly (2008-12-09)

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