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Cancer Weekly

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B-Cell Lymphoma



Research on B-cell lymphoma published by D. Ennishi et al



December 9th, 2008

According to a study from Tokyo, Japan, "Several biomarkers indicating poor prognosis have been reassessed in patients receiving rituximab combination chemotherapy for diffuse large B-cell lymphoma (DLBCL). However, few studies have investigated outcome in relation to a combination of these biomarkers."

"In addition, no large-scale studies have reassessed the outcome of patients with CD5-positive DLBCL treated with rituximab. We conducted a retrospective study and investigated the predictive value of three biomarkers-BCL2, germinal center (GC) phenotype and CD5-in 121 DLBCL patients treated with rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone....


Source: Cancer Weekly (2008-12-09)

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