Cancer Weekly
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Barrett Esophagus
Study results from X.Y. Shi and colleagues in the area of barrett esophagus published
December 9th, 2008
"Barrett esophagus (BE) (BE) is in established precursor of esophageal adenocarcinoma (AdenoCa). One hundred and one cases of BE diagnosed by esophageal biopsy and resections were examined morphologically for dysplasia," investigators in Newcastle, Australia report. "These were categorized as BE without dysplasia (n = 25). indefinite for dysplasia (IND, n = 17). low-grade dysplasia (LGD, it 18)7 high-grade dysplasia (HGD. n=15). and AdenoCa (n= 26). Immunostaining for p16 (INK4A CDKN2A). Cyclin D1 (CCND1). Ki-67. and alpha-methylacyl-CoA racemase (AMACR) was employed to assess their potential as diagnostic discriminators. Abnormal p16 expression (negative. cytoplasmic....
Source: Cancer Weekly (2008-12-09)
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