Cancer Weekly
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Cancer Gene Therapy
Studies from R. Eager and colleagues yield new information about cancer gene therapy
December 9th, 2008
According to recent research published in the journal Expert Opinion on Biological Therapy, "The melanoma differentiation-associated gene-7 (MDA-7) was isolated while screening for upregulated genes in terminally differentiated melanoma cell lines. Preclinical studies attempted to test the theory that oncogenesis arises from a cellular differentiation process culminating in dysregulation of the cell cycle and ultimately malignancy." "The MDA-7 gene (gene symbol IL-24) has been classified as part of the IL-10 family of cytokines demonstrating significant anticancer potential. Preclinical studies have shown that MDA-7/IL-24 is effective in inducing cancer cell...
Source: Cancer Weekly (2008-12-09)
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