Cancer Therapy
Data from Centro de Investigacion y de Estudios Avanzados del IPN provide new insights into cancer therapy
Published in Cancer Weekly, December 16th, 2008
Researchers detail in 'Valproic acid induces polarization, neuronal-like differentiation of a subpopulation of C6 glioma cells and selectively regulates transgene expression,' new data in cancer. "Glioblastoma is the most frequent primary brain tumor, and for which standard therapies have not significantly increased the survival of patients. Recently, chromatin alterations have been linked to the pathogenesis of cancer, and drugs that modify chromatin structure, such as inhibitors of histone deacetylases (iHDAC), are now considered as a valuable strategy for the treatment of cancer," researchers in Mexico report.
"For instance, valproic acid (VPA), an iHDAC originally...
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Source: Cancer Weekly (2008-12-16)
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