Cancer Weekly
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B-Cell Lymphoma
Studies from Duke University update current data on B-cell lymphoma
December 16th, 2008
According to a study from the United States, "The E mu-myc transgenic mouse has provided a valuable model for the study of B-cell lymphoma. Making use of gene expression analysis and, in particular, expression signatures of cell signaling pathway activation, we now show that several forms of B lymphoma can be identified in the E mu-myc mice associated with time of tumor onset." "Furthermore, one form of E mu-myc tumor with pre-B character is shown to resemble human Burkitt lymphoma, whereas others exhibit more differentiated B-cell characteristics and show similarity with human diffuse large B-cell lymphoma in the pattern of gene expression, as well as oncogenic pathway...
Source: Cancer Weekly (2008-12-16)
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