Cancer Weekly
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Breast Cancer
Findings from University of Jena provide new insights into breast cancer
December 16th, 2008
According to recent research from Jena, Germany, " Bone morphogenetic proteins (BMPs) are multifunctional regulators of various cell functions. The BMP-signalling network plays a pivotal role during embryogenesis and tumorigenesis. BMPs, e.g." "BMP-2 exert their biological function in a time and concentration-dependent manner but also modulated by the context of the cellular microenvironment. In this study, we investigated the effect of a steady high level of BMP-2 versus a single application of BMP-2 on the breast cancer cell line MCF-7. The effect of the incubation regimes was analysed by DNA microarray expression profiling. Data were verified by real-time PCR. The...
Source: Cancer Weekly (2008-12-16)
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