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Breast Cancer
New breast cancer study findings have been published by scientists at Nanjing Medical University
December 16th, 2008
According to a study from Nanjing, People's Republic of China, " A satisfactory animal model of breast cancer metastasizing to bone is unavailable. In this study, we used human breast cancer stem-like cells and human bone to build a novel ''human-source'' model of human breast cancer skeletal metastasis." " Human breast cancer stem-like cells, the CD44(+)/CD24(-/lower) subpopulation, was separated and cultured. Before injection with the stem-like cells, mice were implanted with human bone in the right or left dorsal flanks. Animals in Groups A, B, and C were injected with 1x10(5), 1x10(6) human breast cancer stem-like cells, and 1x10(6) parental MDA-MB-231 cells,...
Source: Cancer Weekly (2008-12-16)
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