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Life Sciences
New life sciences study findings recently were reported by researchers at Weizmann Institute of Science, Department of Organic Chemistry
December 23rd, 2008
New investigation results, 'Structure and function of the Pre-mRNA splicing machine,' are detailed in a study published in Structure. According to recent research from Rehovot, Israel, "Most eukaryotic pre-mRNAs contain non-coding sequences (introns) that must be removed in order to accurately place the coding sequences (exons) in the correct reading frame. This critical regulatory pre-mRNA splicing event is fundamental in development and cancer." "It occurs within a mega-Dalton multicomponent machine composed of RNA and proteins, which undergoes dynamic changes in RNA-RNA, RNA-protein, and protein-protein interactions during the splicing reaction. Recent years...
Source: Cancer Weekly (2008-12-23)
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